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Jinkai Zheng Selected Research

nobiletin

4/2020Synergistic anticancer effects of curcumin and 3',4'-didemethylnobiletin in combination on colon cancer cells.
11/2019Inhibitory effects of nobiletin and its major metabolites on lung tumorigenesis.
1/2018A metabolite of nobiletin, 4'-demethylnobiletin and atorvastatin synergistically inhibits human colon cancer cell growth by inducing G0/G1 cell cycle arrest and apoptosis.
1/2017Nobiletin and its colonic metabolites suppress colitis-associated colon carcinogenesis by down-regulating iNOS, inducing antioxidative enzymes and arresting cell cycle progression.
1/2017Synergistic chemopreventive effects of nobiletin and atorvastatin on colon carcinogenesis.
12/2016Label-free Imaging and Characterization of Cancer Cell Responses to Polymethoxyflavones Using Raman Microscopy.
12/2015Inhibitory Effects of 4'-Demethylnobiletin, a Metabolite of Nobiletin, on 12-O-Tetradecanoylphorbol-13-acetate (TPA)-Induced Inflammation in Mouse Ears.
12/2015Anti-inflammatory effects of 4'-demethylnobiletin, a major metabolite of nobiletin.
12/2015Chemopreventive effects of nobiletin and its colonic metabolites on colon carcinogenesis.

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Jinkai Zheng Research Topics

Disease

11Colonic Neoplasms (Colon Cancer)
06/2020 - 10/2011
10Neoplasms (Cancer)
10/2021 - 10/2011
9Carcinogenesis
06/2020 - 12/2015
4Colitis
02/2022 - 12/2015
3Inflammation (Inflammations)
02/2022 - 12/2015
2Atherosclerosis
05/2021 - 11/2020
2Lung Neoplasms (Lung Cancer)
03/2017 - 06/2016
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
06/2016 - 12/2013
1Hyperglycemia
01/2022
1Cardiovascular Diseases (Cardiovascular Disease)
10/2021
1Weight Gain
05/2021
1Atherosclerotic Plaque (Atheroma)
05/2021
1Hyperlipidemias (Hyperlipidemia)
02/2018
1Colorectal Neoplasms (Colorectal Cancer)
02/2018

Drug/Important Bio-Agent (IBA)

9nobiletinIBA
04/2020 - 12/2015
6FlavonoidsIBA
10/2021 - 06/2016
55-demethylnobiletinIBA
06/2020 - 11/2013
4Proteins (Proteins, Gene)FDA Link
06/2020 - 12/2015
4AzoxymethaneIBA
06/2020 - 12/2015
3CurcuminIBA
01/2022 - 04/2020
3Dextran SulfateIBA
06/2020 - 12/2015
3Pharmaceutical PreparationsIBA
02/2018 - 01/2017
3Atorvastatin (Lipitor)FDA Link
02/2018 - 01/2017
2Apolipoproteins E (ApoE)IBA
05/2021 - 11/2020
2naringinIBA
05/2021 - 11/2020
2CholesterolIBA
11/2020 - 02/2018
2gardenin BIBA
01/2020 - 12/2013
24- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA
11/2019 - 03/2017
24'-demethylnobiletinIBA
01/2018 - 12/2015
2LipidsIBA
01/2018 - 01/2017
1AcidsIBA
02/2022
1CellulaseIBA
02/2022
1Dextrans (Dextran)FDA Link
02/2022
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
02/2022
1PectinsIBA
02/2022
1AlkaliesIBA
02/2022
1GlycogenIBA
01/2022
1Glucose (Dextrose)FDA LinkGeneric
01/2022
1Carotenoids (Carotene)IBA
10/2021
1Volatile Oils (Essential Oils)IBA
10/2021
1LimoninsIBA
10/2021
1sinensetinIBA
05/2021
1Orlistat (Xenical)FDA Link
05/2021
1FlavanonesIBA
05/2021
1HesperidinIBA
05/2021
1hesperetinIBA
05/2021
1Bile Acids and Salts (Bile Acids)IBA
05/2021
1naringeninIBA
05/2021
13',4'-didemethylnobiletinIBA
04/2020
1xanthomicrolIBA
01/2020
1PhloretinIBA
02/2018
1LDL Lipoproteins (beta Lipoproteins)IBA
02/2018
1CarcinogensIBA
03/2017
1EnzymesIBA
01/2017
1pinostilbeneIBA
01/2016
1ResveratrolIBA
01/2016
1pterostilbeneIBA
01/2016
1LipopolysaccharidesIBA
12/2015
1Angiogenesis Inducing Agents (Angiogenesis Factor)IBA
10/2011
1matrigelIBA
10/2011
15- hydroxy- 3,6,7,8,3',4'- hexamethoxyflavoneIBA
10/2011

Therapy/Procedure

4Oral Administration
11/2019 - 12/2015
3Chemoprevention
02/2018 - 06/2016